Amended: Updated Quotation Notice - RUARB

This is an amended release of the recently announced updated quotation notice for RUARB. The date mentioned in the text is the rights trading close date instead of closing date of the offer. Refer below for the corrected text. Following the announcement from RUA regarding the extension of closing date for the rights offer from Friday, 28 November 2025 to Friday, 12 December 2025, please see attached an updated Quotation Notice. UPDATED QUOTATION NOTICE: NZX MAIN BOARD RUA BIOSCIENCE LIMITED (“RUARB”) RIGHTS Issuer: Rua Bioscience Limited (“RUA”) Ticker Code: RUARB ISIN: NZRUAE0006S6 Details of Issue: A pro-rata renounceable rights issue of 1 new share for every 3 existing shares held on the Record Date. Ratio (New: Existing): 1 : 3 Exercise Price: NZ$0.025 per new share Reference Price: Calculated as head share price prior to quotation minus the Exercise Price Issue Price Payable: In full on application Registrar: Computershare Investor Services Limited (“RMLT”) Settlement Status: NZCDC Settlement System Key Dates Ex Rights Date: Friday, 7 November 2025 Rights Commence Trading: Friday, 7 November 2025 Record Date: 5pm, Monday, 10 November 2025 Letters of Entitlement sent to Shareholders: Tuesday, 11 November 2025 Offer Opens: Tuesday, 11 November 2025 Rights Quotation Ceases: Monday, 8 December 2025 Offer Closes: Friday, 12 December 2025 Allotment and commencement of trading of New Shares (retail offer): Thursday, 18 December 2025 Mark Peterson Chief Executive Officer NZX Limited 20 November 2025